I'm Cristina, an NMC-registered aesthetic nurse, and I offer polynucleotide treatments across Norwich and Norfolk. This is a cellular regeneration treatment that works from the inside out, helping your skin rebuild itself and look healthier overall. Sessions start at £250 as part of our launch offer, and as a mobile medical aesthetics service in Norwich, I can see you at home, at work, or wherever is convenient for you.
What are Polynucleotides?
Polynucleotides are DNA fragments derived from salmon or trout. When injected into your skin, they trigger your body's natural regeneration process at a cellular level. This stimulates collagen production, improves skin elasticity, and provides deep hydration. The result is skin that looks healthier, more resilient, and visibly rejuvenated.
They're not fillers, so they won't add volume to your face. They also work differently to Profhilo (coming soon to Pardo Medical), which focuses on moisture retention. Instead, polynucleotides work on repairing and regenerating your skin's structure. Most people benefit from a course of two to three sessions spaced three to four weeks apart, allowing your skin time to respond between treatments.
Who is it For?
Polynucleotides are ideal if your skin looks dull or tired, or if you're concerned about fine lines, sun damage, and acne scarring. They work well for anyone wanting to improve their overall skin quality and appearance. The treatment can be used on your face, neck, under-eye area, and hands, which are often neglected but show age.
You don't need obvious signs of ageing to benefit from this treatment. If you want your skin to look fresher, more glowing, and healthier, polynucleotides can help. They're particularly good if you prefer subtle improvement over dramatic change.
What to Expect
Consultation
We start with a video call where we discuss your skin concerns and what you're hoping to achieve. I'll get an initial sense of your skin and talk through the treatment. Then on treatment day, we meet in person for 20 minutes. I'll assess your skin closely, explain how polynucleotides can help with your specific issues, discuss the number of sessions you might need, and walk you through realistic expectations. Once you're ready, we proceed straight to treatment.
Treatment
I'll apply numbing cream first to keep you comfortable. The treatment itself involves a series of small injections across the treatment area. The needles are very fine, and the whole session usually takes about 20 to 30 minutes. You might notice a slight prickling sensation, but it's mild and brief.
Aftercare
Keep the treated area out of direct sun for 24 hours if possible. Avoid saunas, hot baths, and intense exercise for a few days. You might see some mild redness or feel slight tenderness, which is normal and usually settles quickly. I'll give you a full aftercare guide when you finish, and you can reach out if you have any questions.
Results
Improvement happens gradually. You'll likely notice your skin looking healthier and more hydrated within a week or two. Over the following weeks, your skin will appear firmer and more resilient as collagen rebuilds. Fine lines soften, skin texture improves, and your overall complexion becomes more radiant.
Results build with each session in a treatment course. After two or three sessions, the improvement is more noticeable. Effects typically last six to nine months, and you can have another course to maintain the benefits.
Pricing
Polynucleotides start at £250 per session during our launch offer, regular price £300. Most people benefit from a course of two sessions spaced three to four weeks apart, which is £460 during launch (regular price £550). For full pricing and package options, visit our pricing page.
Frequently Asked Questions
They work in different ways. Profhilo hydrates and plumps the skin through moisture retention, and it contains a high concentration of hyaluronic acid. Polynucleotides work at a deeper cellular level by triggering your skin's own regeneration process using DNA fragments. They rebuild collagen and improve overall skin quality rather than adding volume. Profhilo is coming soon to Pardo Medical; polynucleotides are available now.
Most people see the best results with a course of two sessions spaced three to four weeks apart. This allows your skin time to respond to the first treatment and then receive another boost. Some people choose a single session, while others prefer three sessions for more dramatic improvement. We can discuss what works best for your goals during your consultation.
It's relatively comfortable. I use a numbing cream beforehand to reduce sensation, and the needle used for polynucleotides is very fine. Most people describe it as a mild prickling feeling rather than pain. The treatment takes about 20 to 30 minutes, so discomfort is brief. If you're worried about it, just let me know when we chat.
Results typically last between six and nine months. The improvement is gradual, building over several weeks as your skin regenerates. After this time, you can have another session to maintain the benefits. Some people choose to repeat treatments seasonally or when they notice results beginning to fade.
Yes, polynucleotides work well alongside other treatments. They pair beautifully with dermal fillers if you're also looking to add volume, and once Profhilo launches at Pardo Medical you'll be able to combine the two for enhanced hydration and skin quality. We'll discuss what combination might work best for your skin during your consultation.
Ready to explore polynucleotides in Norwich?
Book a consultation to see if this treatment is right for your skin. We'll discuss your goals, answer your questions, and make sure you feel confident about moving forward.
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